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KMID : 1225720160080020174
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Allergy, Asthma & Immunology Research : AAIR
2016 Volume.8 No. 2 p.174 ~ p.177
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The Hidden Culprit: A Case of Repeated Anaphylaxis to Cremophor
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Kim Young-Nam
Kim Jun-Young
Kim Ji-Won
Kim Jin-Hae
Kim Hye-In
Yune Se-Hyo
Choi Dong-Chull
Lee Byung-Jae
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Abstract
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Drug-induced anaphylaxis is a big pitfall in patients receiving antineoplastic chemotherapy. We report a case of lung cancer patient who experienced two near-fatal anaphylactic reactions that resulted from paclitaxel and multivitamin, seperately. Recurrent severe reactions to different agents led to further investigation to which material the patient was hypersensitive. The skin prick test revealed sensitization to cremophor, which is a commonly used emulsifying agent. This case emphasizes the importance of correctly identifying the culprit drug of anaphylaxis to avoid potentially fatal reaction.
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KEYWORD
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Anaphylaxis, paclitaxel, multivitamin, cremophor, hypersensitivity
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